Each post is a discovery. IRDME is the method — the finding is the story. All results link to their pre-registered hash.
Pre-registered cross-species FPL replication in the Drosophila larval connectome (n=2952 neurons, Winding et al. 2023): h1 CONFIRMED Pearson r=0.363 / Spearman rho=0.663, p=0.002. Hub rank order conserved across 600 million years of evolution. Spearman >> Pearson discrepancy is the primary finding. 25/31 pre-registered, p=0.000439.
F12 pre-registered result: the Functional Proximity Law holds across the full C. elegans 302-neuron connectome (n=279 with synapses). 13 of 15 command interneurons from the smaller M_EXT2 study appear in the top-20 hubs — hub identity preserved at 20:1 scale compression.
The C. elegans connectome experiment uses topology alone to identify PVCL and PVCR as primary command interneurons. r = 0.7774, p = 0.004. The layer definitions and node rankings come from White et al. 1986 — fully independent of IRDME. This is true external validation.